Location:
Room 1.20
Ashworth Laboratories II
Phone: +44 (0) 131 651 3617
Email: sarah.ressel[at]ed.ac.uk
2016 – Present PhD student, Institute for Immunity and Infection Research, The University of Edinburgh
Project: The role of small RNAs in respiratory virus infections
2013 – 2016 MSc in Biochemistry and Infection Biology, Technische Universität Braunschweig (Germany)
Masters project: Biochemical characterization of CRISPR-associated nucleases (Charpentier lab, Max Planck Institute for Infection Biology, Berlin, Germany)
2010 – 2013 BSc in Biology, Technische Universität Braunschweig (Germany)
I am interested in the molecular mechanisms of host-pathogen interactions, especially in understanding the role of small non-coding RNAs in viral infections. In my PhD project I aim to decipher the function of small non-coding RNAs in respiratory syncytial virus (RSV) and parainfluenza virus (PIV)- 3 infections (intracellularly but also extracellularly) to identify their therapeutic potential.
Hille, F., Richter, H., Wong, S., BratoviÄ, M., Ressel, S., Charpentier, E. (2018) The Biology of CRISPR-Cas: Backward and Forward. Cell. Elsevier, 172(6), pp. 1239-1259. doi: 10.1016/j.cell.2017.11.032.
McCaskill, J. L., Ressel, S., Alber, A., Redford, J., Power, U. F., Schwarze, J., Dutia, B. M., Buck, A. (2017). Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling. Molecular therapy. Nucleic acids. Elsevier, 7, pp. 256-266. doi: 10.1016/j.omtn.2017.03.008.