Katrina Gordon

Katrina_GordonKatrina Gordon

Location:
Room 2.55
Ashworth Laboratories

Telephone: +44 (0)131 650 8622

Email: kgordon@ed.ac.uk

 

2013 – Present IIIR Edinburgh University, Post doctoral Scientist/Lab manager

2005 – 2013 Wellcome Trust Centre for Cell Biology, Edinburgh University, Post doctoral Scientist

2000 – 2004 Beatson Institute for Cancer Research, Post doctoral Scientist

1996 – 1999 PPL Therapeutics, Cell Biology group, Research Scientist

1992 – 1996 University of Dundee/Roslin Institute, PhD Thesis: “The derivation and characterisation of a conditionally immortalised mouse mammary epithelial cell line using a transgenic approach”

1986 – 1990 University of Edinburgh, BSc (Hons 2:1) Biochemistry

Publications

  1. Burrage, J., Termanis, A., Geissner, A., Myant, K., Gordon, K. and Stancheva, I. (2012). The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells. J.Cell Sci 125:(22):5524-5534
  2. McCaul JA, Gordon KE, Minty F, Fleming J, Parkinson EK (2008). Telomere dysfunction is related to the intrinsic radio-resistance of human oral cancer cells Oral Oncol (3):261-9
  3. Muntoni A,  Fleming J, Gordon KE, Hunter K, McGregor F, Parkinson EK, and Harrison PR. (2003). Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and retinoic acid receptor: but p53 mutations are not necessarily required. Oncogene. 22 (49): 7804-8.
  4. Wootton M, Steeghs K, Watt D, Munro J, Gordon K, Ireland H, Morrison V,  Behan W, and Parkinson EK. (2003). Telomerase alone extends the replicative life-span of human skeletal muscle cells without compromising genomic instabilty. Human Gene Therapy. 14 (15): 1473-87.
  5. Gordon KE, Ireland H, Roberts M, Steeghs K, McCaul JA, MacDonald DG, and Parkinson EK. (2003). High levels of telomere dysfunction bestow a selective disadvantage during the progession of human oral squamous cell carcinomas. Cancer Research. 63 (2): 458-67.
  6. Forsyth NR, Morrison V, Craig NJ, Fitzsimmons SA, Barr NI, Ireland H, Gordon KE, Dowen S, Cuthbert AP, Newbold RF, Bryce SD, and Parkinson EK. (2002). Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4. Oncogene. 21 (33): 5135-47.
  7. Gordon KE, Binas B, Chapman RS, Kurian KM, Clark AJ, Lane BE, and Watson CJ. (2000). A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Research. 2 (3): 222-235.
  8. Watson CJ, Gordon KE, Robertson M. and Clark  A.J. (1991) Interaction of DNA binding proteins with a milk protein promoter in vitro: Identification of a mammary gland specific factor. Nucleic Acid Research. 19: 6603-6610.